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In this part 2, the anti-inflammatory action of cortisol is discussed.

  1. Inflammation means more white blood cells flooding a specific area creating swelling, pain, and tenderness. Cortisol decreases white blood cells migration into inflammatory zones, therefore, decreasing the aforementioned symptoms
  2. Cortisol prevents fibrosis, the accumulation of collagen, thus preventing thick scars, keloids or scleroderma. Cortisol blocks the overproduction of collagen that fills up spaces between cells and tissues
  3. High doses of cortisol, such as in the use of high dose prednisone medication, may cause the immune gland, the thymus, to atrophy. Immune suppression only seems to happen when high doses of cortisol are used, and when its use it is not balanced with specific addition of anabolic hormones, such as DHEA.
  4. Since cortisol has an anti-inflammatory action, it assists in modulating allergies. Individuals who present with allergies almost always have an adrenal deficiency.


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