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LPP TEST: AN ADVANCED EVALUATION OF CHOLESTEROL AND CARDIOVASCULAR RISK

Heart Disease is the leading cause of death in the United States. Cholesterol has historically been used as the standard indicator for cardiovascular disease, being classified as good (HDL) or bad (LDL). However, research has found that it is the lipoprotein particles that carry the cholesterol throughout the body, not the cholesterol within them, that are responsible for key steps in plaque formation in the arteries and the resulting development of cardiovascular disease. There are different sizes of LDL and HDL particles and some are much more dangerous than others. Smaller and more numerous LDL particles have a greater risk of causing cardiovascular disease.

The National Heart, Blood and Lung Institute reports that approximately 50 percent of people that have a heart attack have “normal” cholesterol levels. This is why it is important to evaluate the lipoprotein particles that carry the cholesterol to get an accurate picture of overall risk.

The LPP (Lipoprotein Particle Profile) test evaluates these cholesterol carrying particles to evaluate your risk for developing cardiovascular disease. The National Cholesterol Education Program (NCEP), recommends this more advanced, comprehensive profile to make a true assessment of risk for developing heart disease.

In addition to measuring basic levels of total cholesterol, LDL, HDL and triglycerides, it also evaluates four additional risk markers, including:

  1.  Small, dense LDL: atherogenic particles that easily penetrate the arterial endothelium, causing plaque.
  2. RLP (Remnant Lipoprotein): very atherogenic lipoproteins that don’t need to be oxidized to form plaque.
  3. Lp(a): prothrombotic small, dense LDL.
  4. HDL2b: positively correlates with heart health because it is an indicator of how well excess lipids are removed.
  5. Small, dense LDL: atherogenic particles that easily penetrate the arterial endothelium, causing plaque.
  6. RLP (Remnant Lipoprotein): very atherogenic lipoproteins that don’t need to be oxidized to form plaque.
  7. Lp(a): prothrombotic small, dense LDL.HDL2b: positively correlates with heart health because it is an indicator of how well excess lipids are removed.

The LPP Plus panel also includes additional cardiovascular risk markers, such as, C-Reactive Protein (cardiac) and Homocysteine.

The LPP test allows your doctor to evaluate the most appropriate and effective treatments based on your specific profile. This includes both medications (Statins, Fibrates) and natural treatments (Niacin, Estrogen, Omega-3 fatty acids, lifestyle changes).

This test is recommended for people that have known high cholesterol to further evaluate their risk and optimize treatment protocols. It is also a valuable test for those that have normal cholesterol that want to evaluate their risk for developing cardiovascular disease based on their Lipoprotein Particle Profile. You can have normal cholesterol levels and still have a negative Lipoprotein Particle Profile, increasing your risk for heart disease.

At Arizona Natural Medicine ®, we offer this cutting-edge, comprehensive test to evaluate your risk for cardiovascular disease. Let us know if you would like to assess your heart disease risk and create an individualized plan to prevent heart disease.

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